Increase Validity of Preclinical Pain Research
If you work in drug discovery and development, you are well aware of the failure rate at...
Preclinical Pig Models for Therapeutic Studies
Historically, rodent models have been used for the discovery of various biological mechanisms...
Behavior tests used with the 6-OHDA model of PD, and what they tell us.
6-OHDA lesioned rats exhibit a number of motor behavioral and non-motor impairments which have...
Preclinical Models for Diabetic Neuropathy
Diabetic neuropathies include a range of dysfunctions of the peripheral nerves that can be...
Cell Types Involved in ischemic Neuroinflammation
Post-stroke neuroinflammation is a very complex phenomenon involving multiple resident and...
Cognitive Impairment Neurodegenerative Disease Models
Diseases of the central nervous system are extremely debilitating, increasingly common, and...
Key features of the 6-OHDA model, their benefits and drawbacks
The 6-OHDA model has contributed significantly to our understanding of Parkinson’s Disease and...
Contributions of the 6-OHDA model to understanding and treating PD
The 6-hydroxydopamine (6-OHDA) model of Parkinson’s Disease (PD) was the first model of PD...
Contributions of Preclinical 6OHDA Model to Understanding PD
The 6-hydroxydopamine (6-OHDA) model of Parkinson's Disease (PD) was the first model of PD...
Preclinical Pain Models. Translating to Clinic
Management of acute pain related to surgical intervention, termed postoperative pain, continues...