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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Assessing Subjective Pain | Preclinical Pain Studies

Rodent models of pain such as nerve injury models are important to understand the mechanisms that...

Increase Validity of Preclinical Pain Research

If you work in drug discovery and development, you are well aware of the failure rate at clinical...

Preclinical Pig Models for Therapeutic Studies

Historically, rodent models have been used for the discovery of various biological mechanisms...

Behavior tests used with the 6-OHDA model of PD, and what they tell us.

6-OHDA lesioned rats exhibit a number of motor behavioral and non-motor impairments which have been...

Preclinical Models for Diabetic Neuropathy

Diabetic neuropathies include a range of dysfunctions of the peripheral nerves that can be broadly...

Cell Types Involved in ischemic Neuroinflammation

Post-stroke neuroinflammation is a very complex phenomenon involving multiple resident and...

Cognitive Impairment Neurodegenerative Disease Models

Diseases of the central nervous system are extremely debilitating, increasingly common, and...

Key features of the 6-OHDA model, their benefits and drawbacks

The 6-OHDA model has contributed significantly to our understanding of Parkinson’s Disease and the...