Promoting Diversity for Translational Success
In preclinical efficacy studies, several factors are often overlooked, and it is important to evaluate variables like sex, age, species,...
In Vitro Modeling
The goal of the preclinical development process is to help predict clinical efficacy, emphasizing the importance of studying diseases through models...
The HTX-011 Story
HTX-011 Breakthrough in Pain Management ZYNRELEF, the commercial name for HTX-011, is the first and only FDA-approved extended-release dual-acting...
Wound Healing Models in Pigs
It is important to bridge the gap between lab findings and clinical applications using translational models, ensuring effective translation for human...
Advancing Nerve Injury and Repair Models
Understanding Mechanisms Underlying Neuropathic Pain
Porcine Translational Research
Advancing Beyond Rodent and Non-Human Primate Models While rodent models have contributed significantly to our understanding of various diseases and...
Increase diversity to improve clinical translation and strengthen pain management outcomes.
The goal of preclinical drug development is to identify potential therapeutic compounds and gain an understanding of disease pathways or target...
Development of a new symptomatic neuroma model
Neuroma in humans is a challenging condition that often leads to persistent pain in residual limbs. Despite its prevalence, this condition proves to...