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Nerve Block

A preclinical model of sciatic nerve block. 

Rapid Assessment of Nerve Blocking Agents


Nerve blocking agents are often used to replace general anesthesia in surgery, provide effective post-operative pain control, and reduce opioid-related side effects. The preclinical model of sciatic nerve block enables researchers to directly access and dose to the sciatic nerve and allows the screening of new nerve blocking agents or drugs designed to reverse local analgesia.


The capability can be applied to other neuropathic pain models such as the SNL and CCI models. The ability to access the sciatic nerve directly opens up options for drug developers. For instance, those who are working with ion channel blockers now have the ability to dose directly to the sciatic nerve rather than systemic administration.



If you are ready to discuss how a partnership can fit into your development program, our scientists are eager to explore the possibilities with you. Like many other pharmaceutical and medical device developers, you can rely on predictive preclinical data.

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