<img height="1" width="1" style="display:none;" alt="" src="https://dc.ads.linkedin.com/collect/?pid=217082&amp;fmt=gif">

Neuroscience Laboratory Services

Modified Post-Operative Pain

Nerve Block in Pigs and Rats

Modified Post-Operative Pain Model


Nerve blocking agents are often used to replace general anesthesia in surgery, provide effective post-operative pain control, and reduce opioid-related side effects. The preclinical model of sciatic nerve block enables researchers to directly access and dose to the sciatic nerve and allows the screening of new nerve blocking agents or drugs designed to reverse local analgesia.
The capability can be applied to other neuropathic pain models such as the SNL and CCI models. The ability to access the sciatic nerve directly opens up options for drug developers. For instance, those who are working with ion channel blockers now have the ability to dose directly to the sciatic nerve rather than systemic administration.

Request Study Proposal



Request Study Proposal



3 Sapir Street       
Nes Ziona, Israel

Tel: +972 (8) 939 6884 
Fax: (651) 641 1773

United States

45 Prospect Street        
Cambridge, MA 02139

Tel: (617) 764-6555 
Toll Free: 888-876-3246
Fax: (651) 641 1773