Focal Ischemia (MCAo) Models
There are a number of well-characterized, ischemic stroke models used to study ischemic stroke injury and mechanisms of cell damage. Focal ischemia (MCAo) models are used to mimic human stroke, however the global ischemia (4VO) model is highly relevant in clinical conditions, such as cardiac arrest.
Our stroke models can also be used as a platform for studying effects of therapies on neurodegenerative disorders. The following table describes ischemic stroke models offered by MD Biosciences along with the area of expected damage and relevant cognitive/behavioral tests.
Our scientists are experienced with rapidly validating models from literature, and can work with your study requirements. Contact a scientist to discuss your programs today and to learn how we can help accelerate your research.
Common Models for Stroke Pathophysiology