Rodent Efficacy Models

Preclinical Rodent Models

• Pain Models

  Pain research is a complex field that requires a deep understanding of the neural pathways and mechanisms, as well as the infrastructure needed to develop objective analysis tools and biomarkers. MD Biosciences specializes in pain research and runs models of neuropathic pain, post-operative pain and inflammatory pain.

  Learn more about our extensive experience in pain models.

• Neurodegeneration Models

  Drug development for neurodegenerative diseases requires a multifaceted approach that involves clinically-relevant models and reliable biomarkers that demonstrate disease progression and treatment. MD Biosciences has several neurodegeneration models, and combines behavioral assessments with translational endpoints, like in vivo electrophysiology, to determine mode of action, disease state, and drug efficacy. Models include Multiple Sclerosis, Parkinson’s Disease, and Stroke, to name a few.

  Learn more about neurodegeneration models. 

   

• Neuroinflammation Models

  Inflammation is a key pathological driver in many neurological diseases, including diabetic-induced neuropathy, post-operative pain, multiple sclerosis, spinal cord injury, stroke, and Alzheimer’s. MD Biosciences provides scientific expertise on disease mechanism and the inflammatory response, and designs studies that include relevant inflammatory biomarkers involved in neurodegeneration and pain.

  Learn more about models of neuroinflammation. 

• Wound Healing Models

  Wound healing is influenced by several factors, including inflammatory response, cell proliferation, and scar tissue remodeling. Wound healing is affected by the wound size and type, such as incisional, excisional, and burn wounds. Comorbidities, like diabetes, also play a role in wound healing. Wound healing models at MD Biosciences include in vivo assessments, histology and cytokine analysis.

  Learn more about the models of wound healing.