Rodent Models for Preclinical Pain and Neuroscience Studies

Rodent models with readouts that translate

Rodent models are commonly used for evaluating therapeutics prior to clinical studies. MD Biosciences offers a range of in vivo efficacy models for the study of pain, neurodegeneration, neuroinflammation and wound healing. Behavior assessments and cutting-edge biomarkers are integrated into every study to inform the next development decision.

Pain Models
Neurodegeneration Models

Drug development for neurodegenerative diseases requires a multifaceted approach that involves clinically-relevant models and reliable biomarkers that demonstrate disease progression and treatment. MD Biosciences has several neurodegeneration models, and combines behavioral assessments with translational endpoints, like in vivo electrophysiology, to determine mode of action, disease state, and drug efficacy. Models include Multiple Sclerosis, Parkinson’s Disease, and Stroke, to name a few.

Learn more about neurodegeneration models.
Neuroinflammation Models

Inflammation is a key pathological driver in many neurological diseases, including diabetic-induced neuropathy, post-operative pain, multiple sclerosis, spinal cord injury, stroke, and Alzheimer’s. MD Biosciences provides scientific expertise on disease mechanism and the inflammatory response, and designs studies that include relevant inflammatory biomarkers involved in neurodegeneration and pain.

Learn more about models of neuroinflammation.
Wound Healing Models

Wound healing is influenced by several factors, including inflammatory response, cell proliferation, and scar tissue remodeling. Wound healing is affected by the wound size and type, such as incisional, excisional, and burn wounds. Comorbidities, like diabetes, also play a role in wound healing. Wound healing models at MD Biosciences include in vivo assessments, histology and cytokine analysis.

Learn more about the models of wound healing.