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Experimental Autoimmune Encephalomyelitis (EAE)

For the study of Human Demyelinating Diseases

 

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MD Biosciences leverages cutting-edge experimental autoimmune encephalomyelitis (EAE) models to explore demyelinating diseases similar to Multiple Sclerosis (MS). Our EAE models replicate the relapsing-remitting pattern and progressive disability of MS. We integrate behavior analysis, biomarker analysis, and histology into our studies and go further with advanced electrophysiology to deliver a comprehensive view of how therapies impact neurodegeneration and promote neuroprotection. Discover deeper insights into therapeutic efficacy with our expert approach.

 

EAE Models:

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Scientific Data

Electrophysiology (EP) unveils motor and sensory phenomenons in Neuroinflammatory Diseases such as MS/EAE. By adding electrophysiology to studies, we are able to detect changes in disease severity when clinical scores aren't sensitive enough to reflect changes, predict what may happen in the motor system prior to clinical scores showing changes, and understand the neuroprotective effects of therapeutics. 

electrophysiology in EAE
 

EAE datasheet

 

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At MD Biosciences, we’re not just a service provider—we’re your dedicated partner in drug development. With industry-leading expertise, we offer tailored study designs, translational models, and comprehensive endpoint assessments. Our commitment to short lead times and competitive pricing, combined with our deep scientific knowledge, ensures your research progresses efficiently and effectively. Collaborate with us to turn your scientific vision into reality.

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