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Neuroscience Laboratory Services

Translational Pig Models

Increasing interpretation of preclinical data to the clinic

Pig Models: Improved Clinical Translatability

By utilizing translational models in larger species prior to going to clinical stages, drug developers can increase the success rates of those drugs entering clinical phases.

 

Advantages range from technical to scientific: volume of injection, nerve stimulation, imaging, PK, behavioral changes, skin biomarkers. 

  • System similarities between the pig and human including the cardiovascular, central nervous, immune and digestive systems.
  • Correlation between contracile, metabolic and morphological features in skeletal muscle of humans and pigs.   
  • Pig skin exhibits a higher degree of homology to human skin than murine skin, making the pig a preferable animal model for wound healing studies or studies involving transdermal drug delivery.  

Our scientists are experienced with rapidly validating models from literature, and can work with your study requirements. Contact a scientist to discuss your programs today and to learn how we can help accelerate your research.



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