Porcine Neuropathic Pain

Pig Model of Neuropathic Pain

While rodent models of neuropathic pain have provided value in the research community, translational models in the pig can offer a higher degree of clinical relevance, which is why we also offer such models. 

Advantages (range from technical to scientific)

• Volume of injection, nerve stimulation, imaging, PK, behavioral changes, skin biomarkers. 
• System similarities between the pig and human including the cardiovascular, central nervous, immune and digestive systems.
• Correlation between contracile, metabolic and morphological features in skeletal muscle of humans and pigs.
• Pigs exhibit a higher degree of homology to human skin than murine skin, making the pig a preferable animal model for wound healing studies involving transdermal drug delivery. 
  
  

Available Assessments 

• von Frey
• Motor Function
• Spontaneous Behavior
• Biomarkers
• Histology/IHC
• PK