<img height="1" width="1" style="display:none;" alt="" src="https://px.ads.linkedin.com/collect/?pid=3993628&amp;fmt=gif">

Animal Models of Neuroma 


Models for studying why nerves fail to regenerate, leading to painful neuroma.


Neuroma results from hypercellular and proliferative outgrowth following a nerve injury, such as crush, stretch, or transection. In many cases, the blood-nerve barrier is disrupted leading to allodynia or an increased response of nerves and pain sensitization, causing a pain response from stimuli that doesn't normally provoke pain. 


Animal Models of Neuroma

Speak with a scientist

Neuroma Formation

Sample from day 54 in the mouse Spared Nerve Injury Model (SNI). Composite photo of a nerve (arrows on left) becoming a neuroma (boxed) which grows into the surrounding soft tissue.

Neuroma 3


Histopathological score at 28 and 54 days post surgery. 

Neuroma histo


If you are ready to discuss how a partnership can fit into your development program, our scientists are eager to explore the possibilities with you. Like many other pharmaceutical and medical device developers, you can rely on predictive preclinical data.

Request Proposal