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Neural Connections Blog

 

4 min read

Peripheral Nerve Repair: What the Regeneration Endpoints Actually Tell You

Peripheral nerve repair occupies an unusual position in translational neuroscience. The biology is more permissive than...

3 min read

Osteoarthritis Pain Models: Choosing the Species Before You Choose the Endpoint

Osteoarthritis is one of the largest unmet needs in pain, and one of the most stubborn translational problems in the...

4 min read

Electrophysiology as a Translational Endpoint: Why Nerve Conduction Belongs in More Preclinical Packages

Most preclinical neuroscience programs are still built around two categories of evidence. Behavior tells you what the...

3 min read

Quantitative Histology: What Computational Image Analysis Adds to a Preclinical Package

Histology has always carried a quiet tension. It is the most direct evidence a preclinical study can offer, a look at...

3 min read

The Cuprizone Model: Reading Demyelination and Remyelination Without the Autoimmune Noise

Remyelination has become the most interesting frontier in multiple sclerosis. The approved therapies for relapsing...