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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Behavior tests used with the 6-OHDA model of PD, and what they tell us.

6-OHDA lesioned rats exhibit a number of motor behavioral and non-motor impairments which have been...

Preclinical Models for Diabetic Neuropathy

Diabetic neuropathies include a range of peripheral nerve dysfunctions that can be broadly...

Cell Types Involved in ischemic Neuroinflammation

Post-stroke neuroinflammation is a very complex phenomenon involving multiple resident and...

Cognitive Impairment Neurodegenerative Disease Models

Diseases of the central nervous system are extremely debilitating, increasingly common, and...

Key features of the 6-OHDA model, their benefits and drawbacks

The 6-OHDA model has contributed significantly to our understanding of Parkinson’s Disease and the...

Post-stroke Neuroinflammation | Astrocytes & Microglia

Post-stroke neuroinflammation is a very complex phenomenon involving multiple resident and...

Neuroinflammation following acute ischemic stroke

Cellular and molecular interactions involved in neuroinflammation. Potential targets for improved...

MMPs in ischemic conditions (stroke and myocardial infarct)

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that function to degrade...