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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Preclinical Pain Models. Translating to Clinic

Management of acute pain related to surgical intervention, termed postoperative pain, continues to...

Preclinical Post-operative Pain Model Resembles Human Physiology

The management ofpost-operative painis a challenge for both physicians and patients. In addition...

Pain-related Characteristics in the MIA-induced OA Model

Osteoarthritis (OA) is a widespread condition that affects greater than 70% of the elderly...

Neuroinflammation After Acute ischemic Stroke | Preclinical Models

The most common form of stroke is acute ischemic stroke (approximately 85% of cases), which is...

Overview of Microglial Cells in the CNS

Of the roughly 70% of cells in the central nervous system (CNS) that are glia, appromixately 5-10%...

Behavior-based Preclinical Nerve Injury Model Findings

We get a lot of questions on the various neuropathic pain models and how to choose the one that's...

Pain & Inflammation Linkage | Targets in Overlap

Neuropathic pain presents a wide variety of challenges to researchers, not the least of which is...

Wisely Choose Preclinical Model: Large vs. Small Species

Common models for preclinical efficacy often use rodents as they are readily available, cost...