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Neural Connections Blog

MD Biosciences insights discussing preclinical research in pain, neurodegeneration, and wound healing.

New Developments: Innovative Cold Pain Testing Methods

Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....

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Models of Acute Inflammatory Pain

Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...

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Advancing Parkinson’s Research: Insights from Diverse Disease Models

Parkinson’s Disease (PD) is a progressive neurodegenerative movement disorder that affects millions of people worldwide. PD is characterized by the...

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The Development of Peripheral Nerve Repair Models

Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...

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Inflammatory Biomarker Detection Increases Value in Early Drug Development

Inflammation is a key pathological driver in many neurological diseases. The interplay between the central and peripheral nervous systems and the...

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chemotherapy-induced neuropathy

Preclinical Efficacy Models of Chemotherapy-Induced Peripheral Neuropathy

Chemotherapeutics agents are commonly used to treat cancer, but come with side effects such as neurotoxicity and peripheral neuropathy, which...

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Promoting Diversity for Translational Success

In preclinical efficacy studies, several factors are often overlooked, and it is important to evaluate variables like sex, age, species,...

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