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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Preclinical Pain Models. Translating to Clinic

Management of acute pain related to surgical intervention, termed postoperative pain, continues to...

Preclinical Post-operative Pain Model Resembles Human Physiology

The management of post-operative pain is a challenge for both physicians and patients. In addition...

Pain-related Characteristics in the MIA-induced OA Model

Osteoarthritis (OA) is a widespread condition that affects greater than 70% of the elderly...

Behavior-based Preclinical Nerve Injury Model Findings

We get a lot of questions on the various neuropathic pain models and how to choose the one that's...

Pain & Inflammation Linkage | Targets in Overlap

Neuropathic pain presents a wide variety of challenges to researchers, not the least of which is...

Wisely Choose Preclinical Model: Large vs. Small Species

Common models for preclinical efficacy often use rodents as they are readily available, cost...

Inflammation & Pain Processing: Customizable Preclinical Models

Chronic, destructive inflammation is at the core of a wide variety of diseases and conditions.

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Anti-inflammatory Cytokines | Potential Targets In Neuropathic Pain

We are continuing our series on the immune system, inflammation related factors and potential drup...

Pro-inflammatory Cytokines | Potential Neuropathic Pain Targets

Over the past few weeks we have been reviewing the overlap between the nervous and immune systems....

Neuro/Immune Interactions Along Pain Processing Pathway

Previously we discussed various interactions that occur between the immune and nervous systems...