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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Preclinical Post-operative Pain Model Resembles Human Physiology

The management of post-operative pain is a challenge for both physicians and patients. In...

Pain-related Characteristics in the MIA-induced OA Model

Osteoarthritis (OA) is a widespread condition that affects greater than 70% of the elderly...

Behavior-based Preclinical Nerve Injury Model Findings

We get a lot of questions on the various neuropathic pain models and how to choose the one...

Pain & Inflammation Linkage | Targets in Overlap

Neuropathic pain presents a wide variety of challenges to researchers, not the least of which...

Wisely Choose Preclinical Model: Large vs. Small Species

Common models for preclinical efficacy often use rodents as they are readily available, cost...

Inflammation & Pain Processing: Customizable Preclinical Models

Chronic, destructive inflammation is at the core of a wide variety of diseases and conditions.

Anti-inflammatory Cytokines | Potential Targets In Neuropathic Pain

We are continuing our series on the immune system, inflammation related factors and potential...

Pro-inflammatory Cytokines | Potential Neuropathic Pain Targets

Over the past few weeks we have been reviewing the overlap between the nervous and immune...

Neuro/Immune Interactions Along Pain Processing Pathway

Previously we discussed various interactions that occur between the immune and nervous systems...

Nervous & Immune System Interactions | Preclinical Targets

Some of the most interesting and rapidly developing areas inbiomedical science are those being...