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Preclinical Models of Pain

Reproducible and robust pain models combined with traditional and novel readouts. Short lead times help you speed up the discovery of new pain therapies.

 

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Validated pain models from a neurology focused CRO

MD Biosciences is dedicated to the study of pain and neurodegenerative diseases. The understanding of pain and novel mechanisms requires a deep understanding of the science as well as the resources in terms of expertise and infrastructure to effectively study therapeutic candidates in early and translational phases. 

As with any model, the right selection of species, stimuli, assessments, and end-point analysis leads to a quality study that brings insight into the condition and potential therapeutic. MD Biosciences expertise in study design contributes to predictive data from preclinical studies. 

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Behavior assessments

Evaluating pain from stimuli and resulting emotional responses in non-clinical animals. 

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Electrophysiology

Adds to the understanding of pain, particularly when there is limited mobility as a result of disease. 

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Biomarkers

Clinically relevant biomarkers such as nerve fiber analysis adds insight into neuropathic conditions.

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Preclinical Pain Models

MD Biosciences works extensively in various pain conditions. Please review the categories below to see the various models within the different types of pain. Need help designing the right study? Contact us today. 

Understanding behavior as a result of pain.

Measuring pain is often times straight forward using stimuli and measuring the resulting response. But the clinical situation not only evaluates response to the stimuli but the emotional component that patients report. In animal studies, we must rely on vocalization assessments and tests such as the open field to see how animals exhibit anxiety and behave emotionally as a result of the painful condition. 

Learn more about behavior measurements.

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Download the Neuroscience Discovery Services Catalog

 

Our combination of traditional and established models with biomarkers and other innovative methods can bring more clinical relevance to your preclinical programs. With our short lead times, robust models, reliable and reproducible results, we can help you speed up your discovery timelines.

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READY TO DISCUSS YOUR PROJECT?

If you are ready to discuss how a partnership can support your development program, our scientists are eager to explore the possibilities with you. Like many other pharmaceutical and medical device developers, you can rely on predictive preclinical data when studies are designed right.

 

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