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Acute Inflammatory Pain

Pain associated with tissue injury

 

Acute Inflammatory pain is commonly associated with tissue injury and it manifests itself as an expression of neuronal plasticity consisting of central and peripheral sensitization. Tissue injury causes a release of inflammatory mediators from damaged cells which become central to the initiation of the inflammatory cascade.

 

MD Biosciences offers acute inflammatory pain models that can be extended to evaluate a more chronic inflammatory pain state. We can help you study the release of cytokines and their role in the initiation and maintenance of the inflammatory response along with prostaglandins. Prostaglandins contribute to pain by direct activation of nociceptors and sensitization of primary afferent neurons to bradykinin and other mediators.

Models offered at MD Biosciences

 

READY TO DISCUSS YOUR PROGRAM?

If you are ready to discuss how a partnership can fit into your development program, our scientists are eager to explore the possibilities with you. Like many other pharmaceutical and medical device developers, you can rely on predictive preclinical data.

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