Datasheets | MDB Neurosciences

3 min read

Beyond Rodents: How Translational Pig Models Are De-Risking Pain Programs

May 12, 2026by MD Biosciences

The attrition rate for analgesic compounds remains stubbornly high. By some estimates, fewer than 2% of preclinical...

4 min read

The Göttingen Minipig in GLP Toxicology: A Practical Guide for Program Planning

May 5, 2026by MD Biosciences

Species selection for GLP toxicology is one of those decisions that quietly shapes everything downstream. It influences...

3 min read

In Vitro Is Not Enough: Why Large Animal Models Still Drive Pain Drug Approvals

Apr 28, 2026by MD Biosciences

The last five years have seen remarkable advances in in vitro and ex vivo pain research. Human DRG organoids,...

3 min read

From Pig Model to FDA Approval: Lessons from the ZYNRELEF Story

Apr 23, 2026by MD Biosciences

The gap between preclinical efficacy and clinical success in pain drug development is well-documented and widely...

5 min read

Choosing Your Preclinical Species: How Rodents, Dogs, NHPs, and Pigs Compare in Pain Research

Apr 21, 2026by MD Biosciences

Every preclinical pain program begins with a species decision, which shapes everything downstream, including endpoint...