Datasheets | MDB Neurosciences

3 min read

From Pig Model to FDA Approval: Lessons from the ZYNRELEF Story

Apr 23, 2026by MD Biosciences

The gap between preclinical efficacy and clinical success in pain drug development is well-documented and widely...

5 min read

Choosing Your Preclinical Species: How Rodents, Dogs, NHPs, and Pigs Compare in Pain Research

Apr 21, 2026by MD Biosciences

Every preclinical pain program begins with a species decision, which shapes everything downstream, including endpoint...

2 min read

Sex Differences in Pain Research: What Your Preclinical Program May Be Missing

Apr 13, 2026by MD Biosciences

In 2016, the NIH mandate on sex as a biological variable (SABV) formalized what pain researchers had known for years:...

2 min read

The NaV1.8 Era: What Journavx Means for Pain Drug Development

Apr 8, 2026by MD Biosciences

For the first time in over two decades, the FDA has approved a new class of pain medication. Vertex Pharmaceuticals'...

1 min read

From Preclinical Signal to Clinical Confidence: What Pig Models Reveal That Rodents Can’t

Jan 27, 2026by MD Biosciences

The challenge in translational research is not generating data but generating actionable confidence.

Rodent models...