Neural Connections Blog

MD Biosciences insights discussing preclinical research in pain, neurodegeneration, and wound healing.

translational research

Paw withdrawal in the ZDF model

Type 2 Diabetic Neuropathy in the GLP-1 Era

GLP-1 receptor agonists have substantially reshaped the therapeutic landscape for type 2 diabetes and obesity, and the indications now being pursued...

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Rethinking the Preclinical Package for Chronic Kidney Disease: Why Pigs belong in the conversation

Drug development for chronic kidney disease has entered a more ambitious phase. SGLT2 inhibitors, non steroidal mineralocorticoid receptor...

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From Preclinical Signal to Clinical Confidence: What Pig Models Reveal That Rodents Can’t

The challenge in translational research is not generating data but generating actionable confidence.

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Why Pigs Are Becoming the Preferred Large Animal Model in Pain and Wound Healing Research

Pain and wound healing research demand models that accurately reflect human tissue structure, innervation, and functional recovery. While rodents...

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Use of a Porcine Model for Studying Spinal Cord Injury

At this year’s Society for Neuroscience (SfN) meeting, our team presented a poster highlighting the advantages of using a porcine model to bridge the...

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A Closer Look at Neuroma in Pigs and Sex-Specific Pain Responses

At the forefront of translational large-animal research, our team has developed clinically relevant pig models to study nerve injury and pain....

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International Congress on Neuropathic Pain 2025

We had the opportunity to present at NeuPSIG 2025 in Berlin, sharing our latest findings in neuropathic pain research. The conference offered...

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How Close Are We to Clinical Translation? Large-Animal Models for SCI

Spinal cord injury (SCI) remains one of the most challenging neurological conditions to treat, with few therapies successfully translating from the...

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Approaches to Designing Preclinical Studies That Reflect Clinical Reality

Bridging the gap between preclinical and clinical research remains one of the most pressing challenges in drug development. While early-stage studies...

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