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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

What PD in Vivo Models Revealed About Pathogenesis & Treatment

Parkinson’s Disease (PD) is typically an adult-onset progressive neurodegenerative movement...

EAE Models for Evaluating Neuroprotective Treatment

Cognitive impairment is common in multiple sclerosis (MS), occuring at all stages of disease. It...

Why Post-operative Pain Is Under-Treated

Adequate pain relief following surgical procedures is well-documented to improve the degree and...

Pain Processing: Cation Channel Blockers. Choosing Pain Models

Sodium and calcium cation channel blockers.

Cannabinoid System | A Target For Pain Relief

The body's cannabinoid system consists of two cannabinoid receptors, CB1 and CB2, their endogenous...

α2-adrenergic Agonists & Tricyclic Antidepressants | Pain Model

α2-adrenergic receptors (α2ARs) are found in many areas in throughout the nervous system, but the...