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Neural Connections Blog

MD Biosciences insights discussing preclinical research in pain, neurodegeneration, and wound healing.

inflammatory pain

From Preclinical Signal to Clinical Confidence: What Pig Models Reveal That Rodents Can’t

The challenge in translational research is not generating data but generating actionable confidence.

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Why Pigs Are Becoming the Preferred Large Animal Model in Pain and Wound Healing Research

Pain and wound healing research demand models that accurately reflect human tissue structure, innervation, and functional recovery. While rodents...

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When Rodents Aren’t Enough: How Translational Pig Models Reduce Late-Stage Risk

Drug development rarely fails because a compound lacked activity. More often, it fails because preclinical models failed to predict clinical reality.

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Behavioral Assessments in Preclinical Pain Models

Chronic pain affects 1 in 5 adults in the US, making it one of the most common chronic conditions 1. Approved analgesics often lack efficacy and have...

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Inflammatory Pain Models in Preclinical Research

Arthritic joint pain is a hallmark of inflammatory diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Preclinical models are...

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Models of Acute Inflammatory Pain

Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...

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