Preclinical Models of Diabetic Neuropathy: STZ, High Fat Diet, and the ZDF Rat
Diabetic peripheral neuropathy affects nearly half of people living with diabetes, and it remains one of the harder complications to treat. The...
neuropathic pain
From Acute to Chronic: Where the 2026 Sodium Channel Programs Are Headed
As of August 2026, acute post-surgical pain has an approved non-opioid sodium channel blocker and a second program with published Phase 2b data....
Modeling diabetic neuropathy with mechanistic and translational considerations
Diabetic neuropathy affects nearly half of individuals living with diabetes, yet its underlying biological drivers remain only partially defined....
Critical Endpoints in Preclinical Pain Studies: Behavioral, Biomarker, and Electrophysiology Assessments
Developing effective therapeutics for pain requires selecting endpoints that accurately reflect the biological, functional, and neurophysiological...
A Closer Look at Neuroma in Pigs and Sex-Specific Pain Responses
At the forefront of translational large-animal research, our team has developed clinically relevant pig models to study nerve injury and pain....
International Congress on Neuropathic Pain 2025
We had the opportunity to present at NeuPSIG 2025 in Berlin, sharing our latest findings in neuropathic pain research. The conference offered...
New Poster: Peripheral Nerve injury Models
MD Biosciences attended the Peripheral Nerve Society 2025 and presented on our pig peripheral nerve injury model. The poster presents the development...
Behavioral Assessments in Preclinical Models
Neurological diseases often result in a combination of motor and cognitive deficits. To gain a broader understanding of the underlying biological...
Behavioral Assessments in Preclinical Pain Models
Chronic pain affects 1 in 5 adults in the US, making it one of the most common chronic conditions 1. Approved analgesics often lack efficacy and have...