Pain after surgery remains a significant healthcare challenge. Here, abobot- ulinumtoxinA (aboBoNT-A, Dysport®) was assessed in a post-surgical pain model in pigs. In this study, we assessed mechanical sensitivity, distress behaviors, latency to approach the investigator, and wound inflammation/healing followed by immunohistochemistry and biomarkers to understand the mechanism of action and warrant moving forward with clinical investigation.
