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Translational Model of Post-operative Pain

Evaluating the analgesic activity of AbobotulinumtoxinA to warrant clinical investigation.





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About this webinar:

Pain after surgery remains a significant healthcare challenge. Here, abobot- ulinumtoxinA (aboBoNT-A, Dysport®) was assessed in a post-surgical pain model in pigs. In this study, we assessed mechanical sensitivity, distress behaviors, latency to approach the investigator, and wound inflammation/healing followed by immunohistochemistry and biomarkers to understand the mechanism of action and warrant moving forward with clinical investigation. 

webinar analgesic activity

Mikhail Kalinichev, Ph.D
Head of Translational Science Addex Therapeutics


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