Synaptic Imaging Assay

Synaptic Imaging Assay 

MD Biosciences offers a synaptic imaging assay for evaluating the effect of different treatments on synapse formation and identification. This assay allows the estimation of inhibitory/excitatory synapses ratio and synaptic strength, a powerful method advancing cognition, learning and degenerative disease research and treatment options. 

Unique Readouts:

• Synaptic Count
• Synaptic Strength
• Identification of synapse type (excitatory/inhibitory)

                               Synaptic imaging (Synaptobrevin2) with marker for inhibitory synapses (GAD65), with primary

                               hippocampal neurons from mouse. ** in green: Synapsin lla (Shullman et al,, 2016). 

                           Pre & Post synaptic imaging (Synaptobrevin2 & PSD95), primary hippocampal neurons from rat.

                                 *EGFP-PSD95 viral-vector (courtesy of Professor Noam Ziv).