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Synaptic Imaging Assay

A powerful method for the research of cognition, learning and degenerative disease treatment

 

MD Biosciences offers a synaptic imaging assay for evaluating the effect of different treatments on synapse formation and identification. This assay allows the estimation of inhibitory/excitatory synapses ratio and synaptic strength, a powerful method advancing cognition, learning and degenerative disease research and treatment options. 

 

Unique Readouts

  • Synaptic Count
  • Synaptic Strength
  • Identification of synapse type (excitatory/inhibitory)

GAD65

Synaptic imaging (Synaptobrevin2) with marker for inhibitory synapses (GAD65), with primary hippocampal neurons from mouse. ** in green: Synapsin lla (Shulman et al, 2016). 

GAD-syn-syb

PSD95

Pre & Post synaptic imaging (Synaptobrevin2 & PSD95), primary hippocampal neurons from rat.

*EGFP-PSD95 viral-vector (courtesy of Professor Noam Ziv). 

PSD95 VV+Syb2 AB_Merge3
 

READY TO DISCUSS YOUR PROGRAM?

If you are ready to discuss how a partnership can fit into your development program, our scientists are eager to explore the possibilities with you. Like many other pharmaceutical and medical device developers, you can rely on predictive preclinical data.

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